AB1269 HEARING LOSS – A RARE MANIFESTATION OF THE CALCIUM PYROPHOSPHATE DIHYDRATE DEPOSITION DISEASE

Background Calcium pyrophosphate dihydrate (CaPPD) deposition disease is a illness with wide range of manifestations from acute gout-like episodic arthritis to an accentuated osteoarthritis picture. A common feature the CaPPD crystals in tissues. Middle ear involvement rare manifestation disease, described few case reports. Objectives Methods Histological examination operating specimen. HRCT. Results 71-year-old man, athlete (tennis, cycling) underwent partial menisectomy 2008 for knee blockade, October 2022 he suffered polytrauma after traffic injury. Het treated arterial hypertension. He has never had inflammatory arthritis, joint problems only connection sports injuries. Last 12 months observed gradually progressing hearing loss, mild dizziness and tinnitus. HRCT scull base demonstrated left-sided osteoma fixation malleus. Tumor mass was removed by surgery. Histology proved calcium material. We have not hyperparathyroidism, hypomagnesemia, or any other primary associated deposition. During subsequent X-ray examination, we found chondrocalcinosis menisci both knees. Conclusion Deposits middle region are disease. Clinically, progressive loss may occur, morphologically resemble be clinical signs underlying Reference [1]Serrano MG et al: J Royal Soc Med open 2020;11:1-4 Acknowledgements: NIL. Disclosure Interests None Declared.